Introduction
Name： YANG Ying
Biography
2025.08-Present, Professor, China National Center for Bioinformation
2024.04-2025.08, Young Investigator, China National Center for Bioinformation
2023.03-2024.04, Young Investigator, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation
2019.11-2023.03, Associate professor, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation
2018.05-2019.11, Associate Professor, Beijing Institute of Genomics, Chinese Academy of Sciences
2014.07-2018.05, Assistant Professor, Beijing Institute of Genomics, Chinese Academy of Sciences
2009.09-2014.07, Doctor of Philosophy (Ph.D.), Beijing Institute of Genomics, Chinese Academy of Sciences
2005.09-2009.07, Bachelor of Science (B.S.), Shandong University, China
Introduction
Dr. Ying Yang is the Professor at the China National Center for Bioinformation. She earned her Bachelor of Science in Biotechnology from Shandong University in 2009 and her Ph.D. in Genomics from the Beijing Institute of Genomics, Chinese Academy of Sciences, under the supervision of Dr. Yun-Gui Yang, in 2014. She has conducted her scientific research at Beijing Institute of Genomics, Chinese Academy of Sciences since 2014.
Her research interests mainly focus on (1) pioneering new technologies in single-cell and spatially resolved RNA multi-omics sequencing and bioinformatics analysis to generate high-quality datasets; (2) utilizing these resources to build an AI-ready corpus for RNA multi-omics, providing a foundational data infrastructure; and (3) developing integrated analysis algorithms to decode spatiotemporal dynamics and precise regulatory mechanisms. She has published over 60 papers (first/co-first: 16; corresponding/co-corresponding: 18) on peer-reviewed journals, including Nature, Molecular Cell, Nature Cell Biology, Cell Research, Nature Communications, etc. She has been selected as a member of the Beijing Nova Program (2020) and an excellent member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2022), also a member of the youth editorial board of Journals including Genomics, Proteomics & Bioinformatics, The Innovation, Science China Life Sciences, and the youth committee member of the RNA branch of the Chinese Society of Biochemistry and Molecular Biology.
Research Fields
1. Multi-omics technologies and bioinformatics
2. RNA biology
Selected Publications
1. Liu Fan#; Wang Mengke#; Gao Suwei#; Song Gege; Liu Mengyao; Li Ying; Sun Piao; Lai Weiyi; Wang Hailin; Yang Yun-Gui*; Liu Feng*; Yang Ying*; Wang Lu*; RNA m5C methylation mediated by Ybx1 ensures hematopoietic stem and progenitor cell expansion; Cell Reports, 2025, 44(2):115324. (Cell Reports cover story)
2. Cui Guanshen#; Zhou Jia-Yi#; Ge Xin-Yang#; Sun Bao-Fa#; Song Ge-Ge#; Wang Xing#; Wang Xiu-Zhi; Zhang Rui; Wang Hai-Lin; Jing Qing; Zhao Yong-Liang; Koziol Magdalena J; Zeng An; Zhang Wei-Qi*; Han Da-Li*; Yang Yun-Gui*; Yang Ying*; m6A promotes planarian regeneration, Cell Proliferation, 2023, e13481.
3. Yao Huan#; Gao Chun-Chun#; Zhang Danru#; Xu Jiawei#; Song Gege; Fan Xiu; Liang Dao-Bo; Chen Yu-Sheng; Li Qian; Guo Yanjie; Hu Lulu; Zhao Yongliang; Sun Yingpu; Yang Ying*; Han Jianyong*; Yang Yun-Gui*; scm6A-seq reveals single-cell landscapes of the dynamic m6A during oocyte maturation and early embryonic development, Nature Communications, 2023, 14(1):315.
4. Yang Wen-Lan#; Qiu Weinan#; Zhang Ting#; Xu Kai#; Gu Zi-Juan#; Zhou Yu; Xu Heng-Ji; Yang Zhong-Zhou; Shen Bin; Zhao Yong-Liang; Zhou Qi; Yang Ying*; Li Wei*; Yang Peng-Yuan*; Yang Yun-Gui*; Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis, Nature Communications, 2023, 14(1):863.
5. Shi Boyang#; Heng Jian#; Zhou Jia-Yi#;Yang Ying#; Zhang Wan-Ying; Koziol Magdalena J; Zhao Yong-Liang; Li Pilong; Liu Feng*; Yang Yun-Gui*; Phase separation of Ddx3xb helicase regulates maternal-to-zygotic transition in zebrafish,Cell Research,2022, 32(8):715-728.
6. Yao Yingpeng#; Yang Ying#; Guo Wenhui#; Xu Lifan#; You Menghao; Zhang Yi-Chang; Sun Zhen; Cui Xiao; Yu Guotao; Qi Zhihong; Liu Jingjing; Wang Fang; Liu Juanjuan; Zhao Tianyan; Ye Lilin*; Yang Yun-Gui*; Yu Shuyang*; METTL3-dependent m6A modification programs T follicular helper cell differentiation, Nature Communications, 2021, 12(1):1333.
7. Zhang Ting#; Yang Ying#; Xiang Zichun#; Gao Chun-Chun#; Wang Wenjing; Wang Conghui; Xiao Xia; Wang Xing; Qiu Wei-Nan; Li Wen-Jie; Ren Lili; Li Mingkun; Zhao Yong-Liang; Chen Yu-Sheng*; Wang Jianwei*; Yang Yun-Gui*; N6-methyladenosine regulates RNA abundance of SARS-CoV-2, Cell Discovery, 2021, 7(1):7.
9. Yang Ying#; Wang Lu#; Han Xiao#; Yang Wen-Lan#; Zhang Mengmeng#; Ma Hai-Li; Sun Bao-Fa; Li Ang; Xia Jun; Chen Jing; Heng Jian; Wu Baixing; Chen Yu-Sheng; Xu Jia-Wei; Yang Xin; Yao Huan; Sun Jiawei; Lyu Cong; Wang Hai-Lin; Huang Ying; Sun Ying-Pu; Zhao Yong-Liang; Meng Anming; Ma Jinbiao*; Liu Feng*; Yang Yun-Gui*; RNA 5-methylcytosine facilitates the maternal-to-zygotic transition by preventing maternal mRNA decay, Molecular Cell, 2019, 75(6):1188-1202.
10. Chen Xin#; Li Ang#; Sun Bao-Fa#; Yang Ying#; Han Ya-Nan#; Yuan Xun#; Chen Ri-Xin; Wei Wen-Su; Liu Yanchao; Gao Chun-Chun; Chen Yu-Sheng; Zhang Mengmeng; Ma Xiao-Dan; Liu Zhuo-Wei; Luo Jun-Hang; Lyu Cong; Wang Hai-Lin; Ma Jinbiao; Zhao Yong-Liang; Zhou Fang-Jian; Huang Ying*; Xie Dan*; Yang Yun-Gui*; 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs, Nature Cell Biology, 2019, 21(8):978-990. (Selected by Editorial Comment of The Journal of Urology)
11. Yang Ying#; Hsu Phillip J.#; Chen Yu-Sheng; Yang Yun-Gui*; Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism, Cell Research, 2018, 28(6):616-624.
12. Zhang Chunxia#; Chen Yusheng#; Sun Baofa#; Wang Lu#; Yang Ying#; Ma Dongyuan; Lv Junhua; Heng Jian; Ding Yanyan; Xue Yuanyuan; Lu Xinyan; Xiao Wen; Yang Yun-Gui*; Liu Feng*; m6A modulates haematopoietic stem and progenitor cell specification, Nature, 2017, 549(7671):273-276. (Highlighted by the Journal of Genetics and Genomics and Science Signaling)
13. Yang Xin#; Yang Ying#; Sun Bao-Fa#; Chen Yu-Sheng#; Xu Jia-Wei#; Lai Wei-Yi#; Li Ang; Wang Xing; Bhattarai Devi Prasad; Xiao Wen; Sun Hui-Ying; Zhu Qin; Ma Hai-Li; Adhikari Samir; Sun Min; Hao Ya-Juan; Zhang Bing; Huang Chun-Min; Huang Niu; Jiang Gui-Bin; Zhao Yong-Liang; Wang Hai-Lin*; Sun Ying-Pu*; Yang Yun-Gui*; 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader, Cell Research, 2017, 27(5):606-625. (Cell Research cover story，highlighted by Cell Research and National Science Review, recommended by F1000)
14. Xu Kai#; Yang Ying#; Feng Gui-Hai#; Sun Bao-Fa#; Chen Jun-Qing#; Li Yu-Fei; Chen Yu-Sheng; Zhang Xin-Xin; Wang Chen-Xin; Jiang Li-Yuan; Liu Chao; Zhang Ze-Yu; Wang Xiu-Jie; Zhou Qi*; Yang Yun-Gui*; Li Wei*; Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation, Cell Research, 2017, 27(9):1100-1114. (Cell Research cover story)
15. Zhao Xu#; Yang Ying#; Sun Bao-Fa#; Shi Yue#; Yang Xin; Xiao Wen; Hao Ya-Juan; Ping Xiao-Li; Chen Yu-Sheng; Wang Wen-Jia; Jin Kang-Xuan; Wang Xing; Huang Chun-Min; Fu Yu; Ge Xiao-Meng; Song Shu-Hui; Jeong Hyun Seok; Yanagisawa Hiroyuki; Niu Yamei; Jia Gui-Fang; Wu Wei; Tong Wei-Min; Okamoto Akimitsu; He Chuan; Rendtlew Danielsen Jannie M; Wang Xiu-Jie; Yang Yun-Gui*; FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis, Cell Research, 2014, 24(12):1403-1419. (Highlighted by Cell Research)
Awards and Honors
2022-2025, Highly Cited Researcher (Clarivate)
2024, Second Prize of Natural Science Award, Beijing Science and Technology Award (3rd contributor)
2022, Excellent member of the Youth Innovation Promotion Association of CAS
2020, Member of Beijing Nova Program
2017, Top 10 Research Advances in Life Sciences in China (Co-first author)
2017, Sanofi–Cell Research Outstanding Paper Award (Co-first author)
Contact or Others
Email: yingyang@cncb.ac.cn
