Professional Experience
Associate Director of BIG data center, Beijing Institute of Genomics, Chinese Academy of Sciences, China, 2016-Present
Bioinformatics Principle Engineer, Beijing Institute of Genomics (BIG), Chinese Academy of Sciences, Beijing, China, 2008-Present
Manager, Softbrain Software (Beijing) Co., Ltd., Beijing, China, 2004-2008
Project Manager, Beijing Genomics Institute (BGI), Beijing, China, 2001–2004
Education
M.S. in Computer & Engineering, Beihang University, Beijing, China, 2008
B.S. in Computer Technology & Application, Xi'an Technological University, Xi'an, China, 2001
Research Interests
NGS data analysis, data mining and data visualization
Bioinformatics Databases
High Performance Computing
Projects & Resources
wapRNA: A web based application for RNA analysis (http://waprna.big.ac.cn)
LIMS: Labortary Information Management System (http://lims.big.ac.cn)
Omics database (http://www.omics.csdb.cn)
WBSA: web service for bisulfite-sequencing data analysis (http://wbsa.big.ac.cn)
The Dog SNP database (http://dogsd.big.ac.cn)
The Sorghum SNP database (http://sorgsd.big.ac.cn)
BioCloud (http://biocloud.big.ac.cn)
GSA: Genome Sequence Archive (http://gsa.big.ac.cn)
Selected Publications
1. Luo H, Zhao W, Wang Y, Xia Y, Wu X, Zhang L, Tang B, Zhu J, Fang L, Du Z, Bekele WA, Tai S, Jordan DR, Godwin ID, Snowdon RJ, Mace ES, Jing HC, Luo J: SorGSD: a sorghum genome SNP database. Biotechnol Biofuels 2016, 9:6. [PMID=26744602]
2. Bai B, Zhao WM, Tang BX, Wang YQ, Wang L, Zhang Z, Yang HC, Liu YH, Zhu JW, Irwin DM, Wang GD, Zhang YP: DoGSD: the dog and wolf genome SNP database. Nucleic Acids Research 2015, 43(D1):D777-D783. [PMID=25404132]
3. Tang B, Wang Y, Zhu J, Zhao W: Web resources for model organism studies. Genomics, proteomics & bioinformatics 2015, 13(1):64-68. [PMID=25707592]
4. Ding J, Zhao L, Chang Y, Zhao W, Du Z, Hao Z:Transcriptome sequencing and characterization of Japanese scallop Patinopecten yessoensis from different shell color lines. PLoS One 2015,10(2):e0116406. [PMID=25680107]
5. Li B, Zong Y, Du Z, Chen Y, Zhang Z, Qin G, Zhao W, Tian S:Genomic characterization reveals insights into patulin biosynthesis and pathogenicity in Penicillium species.Mol Plant Microbe Interact 2015,28(6):635-47. [PMID=25625822]
6. Di R, He J, Song S, Tian D, Liu Q, Liang X, Ma Q, Sun M, Wang J, Zhao W, Cao G, Wang J, Yang Z, Ge Y, Chu M:Characterization and comparative profiling of ovarian microRNAs during ovine anestrus and the breeding season. BMC Genomics 2014,15:899. [PMID=25318541]
7. Liang F, Tang B, Wang Y, Wang J, Yu C, Chen X, Zhu J, Yan J, Zhao W, Li R:WBSA: web service for bisulfite sequencing data analysis. PloS one 2014, 9(1):e86707.[PMID=24497972]
8. Wang GD, Zhai W, Yang HC, Fan RX, Cao X, Zhong L, Wang L, Liu F, Wu H, Cheng LG, Poyarkov AD, Poyarkov NA Jr, Tang SS, Zhao WM, Gao Y, Lv XM, Irwin DM, Savolainen P, Wu CI, Zhang YP:The genomics of selection in dogs and the parallel evolution between dogs and humans. Nature Communications 2013,4:1860. [PMID=23673645]
9. Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, V?gb? CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C:ALKBH5 is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.Molecular Cell 2013,49(1):18-29. [PMID=23177736]
10. Zhao W, Liu W, Tian D, Tang B, Wang Y, Yu C, Li R, Ling Y, Wu J, Song S, Hu S: wapRNA: a web-based application for the processing of RNA sequences. Bioinformatics 2011, 27(21):3076-3077. [PMID=21896507]
11. Tao Y, Ruan J, Yeh SH, Lu X, Wang Y, Zhai W, Cai J, Ling S, Gong Q, Chong Z, Qu Z, Li Q, Liu J, Yang J, Zheng C, Zeng C, Wang HY, Zhang J, Wang SH, Hao L, Dong L, Li W, Sun M, Zou W, Yu C, Li C, Liu G, Jiang L, Xu J, Huang H, Li C, Mi S, Zhang B, Chen B, Zhao W, Hu S, Zhuang SM, Shen Y, Shi S, Brown C, White KP, Chen DS, Chen PJ, Wu CI:Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A 2011,108(29):12042-7. [PMID=21730188]
12. Zhou R, Ling S, Zhao W, Osada N, Chen S, Zhang M, He Z, Bao H, Zhong C, Zhang B, Lu X, Turissini D, Duke NC, Lu J, Shi S, Wu CI:Population genetics in nonmodel organisms: II. natural selection in marginal habitats revealed by deep sequencing on dual platforms. Mol Biol Evol 2011,28(10):2833-42. [PMID=21504891]
13. Yu J, Wang J, Lin W, Li S, Li H, Zhou J, Ni P, Dong W, Hu S, Zeng C, Zhang J, Zhang Y, Li R, Xu Z, Li S, Li X, Zheng H, Cong L, Lin L, Yin J, Geng J, Li G, Shi J, Liu J, Lv H, Li J, Wang J, Deng Y, Ran L, Shi X, Wang X, Wu Q, Li C, Ren X, Wang J, Wang X, Li D, Liu D, Zhang X, Ji Z, Zhao W, Sun Y, Zhang Z, Bao J, Han Y, Dong L, Ji J, Chen P, Wu S, Liu J, Xiao Y, Bu D, Tan J, Yang L, Ye C, Zhang J, Xu J, Zhou Y, Yu Y, Zhang B, Zhuang S, Wei H, Liu B, Lei M, Yu H, Li Y, Xu H, Wei S, He X, Fang L, Zhang Z, Zhang Y, Huang X, Su Z, Tong W, Li J, Tong Z, Li S, Ye J, Wang L, Fang L, Lei T, Chen C, Chen H, Xu Z, Li H, Huang H, Zhang F, Xu H, Li N, Zhao C, Li S, Dong L, Huang Y, Li L, Xi Y, Qi Q, Li W, Zhang B, Hu W, Zhang Y, Tian X, Jiao Y, Liang X, Jin J, Gao L, Zheng W, Hao B, Liu S, Wang W, Yuan L, Cao M, McDermott J, Samudrala R, Wang J, Wong GK, Yang H:The Genomes of Oryza sativa: a history of duplications. PLoS Biol 2005,3(2):e38. [PMID=15685292]
14. Wong GK, Liu B, Wang J, Zhang Y, Yang X, Zhang Z, Meng Q, Zhou J, Li D, Zhang J, Ni P, Li S, Ran L, Li H, Zhang J, Li R, Li S, Zheng H, Lin W, Li G, Wang X, Zhao W, Li J, Ye C, Dai M, Ruan J, Zhou Y, Li Y, He X, Zhang Y, Wang J, Huang X, Tong W, Chen J, Ye J, Chen C, Wei N, Li G, Dong L, Lan F, Sun Y, Zhang Z, Yang Z, Yu Y, Huang Y, He D, Xi Y, Wei D, Qi Q, Li W, Shi J, Wang M, Xie F, Wang J, Zhang X, Wang P, Zhao Y, Li N, Yang N, Dong W, Hu S, Zeng C, Zheng W, Hao B, Hillier LW, Yang SP, Warren WC, Wilson RK, Brandstr?m M, Ellegren H, Crooijmans RP, van der Poel JJ, Bovenhuis H, Groenen MA, Ovcharenko I, Gordon L, Stubbs L, Lucas S, Glavina T, Aerts A, Kaiser P, Rothwell L, Young JR, Rogers S, Walker BA, van Hateren A, Kaufman J, Bumstead N, Lamont SJ, Zhou H, Hocking PM, Morrice D, de Koning DJ, Law A, Bartley N, Burt DW, Hunt H, Cheng HH, Gunnarsson U, Wahlberg P, Andersson L, Kindlund E, Tammi MT, Andersson B, Webber C, Ponting CP, Overton IM, Boardman PE, Tang H, Hubbard SJ, Wilson SA, Yu J, Wang J, Yang H:A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature 2004,432(7018):717-22. [PMID=15592405]
15. Zhao W, Wang J, He X, Huang X, Jiao Y, Dai M, Wei S, Fu J, Chen Y, Ren X, Zhang Y, Ni P, Zhang J, Li S, Wang J, Wong GK, Zhao H, Yu J, Yang H, Wang J:BGI-RIS: an integrated information resource and comparative analysis workbench for rice genomics. Nucleic Acids Res 2004,32:D377-82. [PMID=14681438]
16. Yu J, Hu S, Wang J, Wong GK, Li S, Liu B, Deng Y, Dai L, Zhou Y, Zhang X, Cao M, Liu J, Sun J, Tang J, Chen Y, Huang X, Lin W, Ye C, Tong W, Cong L, Geng J, Han Y, Li L, Li W, Hu G, Huang X, Li W, Li J, Liu Z, Li L, Liu J, Qi Q, Liu J, Li L, Li T, Wang X, Lu H, Wu T, Zhu M, Ni P, Han H, Dong W, Ren X, Feng X, Cui P, Li X, Wang H, Xu X, Zhai W, Xu Z, Zhang J, He S, Zhang J, Xu J, Zhang K, Zheng X, Dong J, Zeng W, Tao L, Ye J, Tan J, Ren X, Chen X, He J, Liu D, Tian W, Tian C, Xia H, Bao Q, Li G, Gao H, Cao T, Wang J, Zhao W, Li P, Chen W, Wang X, Zhang Y, Hu J, Wang J, Liu S, Yang J, Zhang G, Xiong Y, Li Z, Mao L, Zhou C, Zhu Z, Chen R, Hao B, Zheng W, Chen S, Guo W, Li G, Liu S, Tao M, Wang J, Zhu L, Yuan L, Yang H:A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science 2002,296:79-92. [PMID=11935017]
17. BIG Data Center Members: The BIG Data Center: from deposition to integration to translation. Nucleic Acids Research 2017, 45(D1):D18-D24. [PMID: 27899658]
18. Wang Y, Song F, Zhu J, Zhang S, Yang Y, Chen T, Tang B, Dong L, Ding N, Zhang Q, Bai Z, Dong X, Chen H, Sun M, Zhai S, Sun Y, Yu L, Lan L, Xiao J, Fang X, Lei H, Zhang Z, Zhao W: Genomics Proteomics Bioinformatics 2017, 15(1):14-18. [PMID: 28387199]
Group Members:
Staff:
CHEN Huanxin, CHEN Tingting, DONG Lili, LAN Li, SUN Yubin, TANG Bixia, WANG Yanqing, YU Lei, ZHAI Shuang, ZHU Junwei, ZHANG Sisi
Graduate Students：
ZHOU Qing, 2016
